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14.2 Obstructive Sleep Apnea Studies in Adults with Obesity Overview of Study 5 and Study 6 The efficacy of ZEPBOUND for moderate to severe obstructive sleep apnea (OSA) (apnea-hypopnea index [AHI] 15) in patients with obesity (BMI 30 kg/m2) was evaluated in a master protocol clinical trial (NCT05412004) that included two randomized, double-blind, placebo-controlled trials (Study 5 and Study 6) of 52 weeks duration

Mitochondrial stress induced by continuous stimulation under hypoxia rapidly drives T cell exhaustion

NAD+ Injections NAD+, nicotinamide adenine dinucleotide, is a coenzyme that naturally occurs in the body