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The development of senolytic drugs demonstrated that targeting these cells limits the deterioration of patients condition, by inducing apoptosis

This receptor modulation triggers a cascade of intracellular signaling events that ultimately result in the activation of hormone-sensitive lipase, the enzyme responsible for breaking down stored triglycerides into free fatty acids and glycerol

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To determine the potential of the peptide, transplantation in some murine models occurred in the presence of ARA-290 while the rest was in the absence of peptides