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The body breaks down peptides via proteolytic enzymes in the blood, liver, and kidneys meaning smaller peptides often have shorter half-lives

J Mol Endocrinol (2014) 53(1):10515

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Key areas of research: Growth Hormone Research IGF-1 Research Endocrinology Research Ghrelin Receptor Research Metabolic Research Healthy Aging Research Hormonal Signaling Research Pituitary Function Research Cellular Recovery Research Growth Hormone Secretagogue Research References Ipamorelin, the First Selective Growth Hormone Secretagogue Growth Hormone-Releasing Peptides and Receptor Selectivity Research References are provided for research context only and do not constitute medical claims