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According to a study published in the Journal of Clinical Psychopharmacology , long-term use of stimulants like Vyvanse results in significant tolerance and dependence (Kripke et al., Hypnotics Association with Mortality or Cancer, 2012)

Veteran organizations and psychedelic advocates have long contended that the ibogaine, which is made from a shrub native to West Africa, has great promise for hard-to-treat conditions such as post-traumatic stress disorder and opioid addiction.

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