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Its primary mechanism of action is the upregulation of brain-derived neurotrophic factor (BDNF), a protein that supports neuronal survival, synaptic plasticity, and the formation of new neural connections

In contrast to the proposed approach, many commenters indicated that the current MS-DRG cost-based methodology established in the FY 2007 IPPS rulemaking is a longstanding and better framework for improving the MS-DRG relative weights consistent with the statute

*Correspondence: Lydia C