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When amylin binds to these receptors, it triggers a cascade that makes you feel full sooner, slows the rate at which food leaves your stomach, and reduces the hedonic drive to eat, the pleasure-seeking component that makes high-calorie foods irresistible

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It also depends on how the numbers are measuredclinical trials report weight loss using different estimands (essentially, different ways of calculating average results), which is why youll sometimes see slightly different percentages for the same study

The FDA is not bound by the panels recommendations