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A double-blind randomized controlled trial that divided healthy subjects into four groups with or without wheat bran (WB) and barley (BM) for a 4-week intervention found that the WB intake group had significantly higher fecal butyrate concentrations and a greater abundance of butyrate-producing bacteria (such as Ruminococcus , Faecalibacterium , and Roseburia ) compared to the non-WB group

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It also may support the nervous system in many ways beyond its role in energy production, including affecting neurotransmitter production and secretion