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Magnetic Resonance-based Response Assessment and Dose Adaptation in Human Papilloma Virus Positive Tumors of the Oropharynx treated with Radiotherapy (MR-ADAPTOR): An R-IDEAL stage 2a-2b/Bayesian phase II trial

Thus, comorbidities like CKD narrow the therapeutic options and require closer monitoring for adverse effects, such as hyperkalemia or changes in renal function