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But its known mechanisms of action have revealed a much broader potential

The side effects might be either due to high dose of vitamin B12 or allergic reaction to its composition

Journal of orthopaedic research, 28 (9), 1155-1161

Given the importance of the cofactor in energy metabolism, NAD + is especially important in mitochondrial function, and in fact both NAD + and mitochondria are concentrated in energetically demanding tissues 10,11,12