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Because the cypionate ester permits a lower injection frequency, hormonal peaks are blunted, which may reduce the incidence of estrogen-related headaches and cyclic mastalgia observed with short-acting formulations, although inter-individual variation remains and careful titration is still recommended to optimize benefit-risk balance

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Quick Tips May interact with certain medications like anti-tuberculosis agents (isoniazid), heavy metal antagonists (penicillamine), vasodilators (hydralazine), and diuretics (furosemide)