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A systematic review and meta-analysis study

The proposed mechanism involves PCs activating peroxisome proliferator-activated receptor (PPAR) in macrophages, upregulating PPAR target genes (CD36 and ABCG1) and driving the transition from M1 to M2 phenotypes

Oxidative stress in liver injury ROS include the free radicals superoxide (O 2 - ) and hydroxyl radical (HO - ) and non-radicals such as hydrogen peroxide (H 2 O 2 )