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For women of reproductive age who may also be on metformin for PCOS, or who are pregnant or breastfeeding, the risk compounds further

Patients should compare total cost across alternatives, including modern combination protocols, when planning a 6 to 12 month treatment cycle

H., Chim, H., Gygi, S

This could be attributed to the high antioxidant activity, accessibility, and reactivity of ascorbic acid with H 2 O 2 compared to the extracts, which contain several antioxidant components that may not act synergistically to exert considerable scavenging action