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In addition, several genes whose downregulation is known to induce lipid accumulation were also specifically downregulated in non-treated SL flies (Fig

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Antibody-conjugated fluorescein exhibits greater specificity than EBD due to its weaker nonspecific binding to plasma proteins, making its systemic distribution highly dependent on the plasma concentration of the antibody target molecule 167

This suggests that modulating ferroptosis in these 3 cell types plays an important role in depression (Figure 2)