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As the cleavage of GSSG with the aid of glutathione reductase produces GSH, which turns on the fluorescence of TPE-DCV, the ensemble of TPE-DCV and GSSG can thus serve as a label-free sensor for enzymatic activity assay of glutathione reductase

Typically, however, treatment for hypothyroidism starts with T4-only formulations, based on the assumption that the body will successfully convert T4 into T3 on its own