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This seems to explain why saturated fatty acids have been implicated in promoting ferroptosis, as they are reduced by FAR1 to the alcohol precursor of ether lipids, i.e., the plasmanyl forms which exacerbate ferroptosis, with subsequent addition of polyunsaturated fatty acids into position sn -2 of phospholipids, although the latter are not the important factor in this instance

Ophthalmic exclusion criteria In the affected eye: Prior corneal surgery (for example, refractive surgery, cataract, collagen crosslinking, endothelial keratoplasty, etc.)