enzyme-catalysed conjugations of glutathione with unsaturated compound doi Glutathione-Mediated Conjugation Anticancer Drugs: An Overview of Reaction Mechanisms and Biological Significance for Drug Detoxification and Bioactivation Phase II Detoxification Enzymes |

(2012) demonstrated that long-term exposure to CP impaired autophagy leading to CP resistance, and interestingly, upregulation of autophagic response under such condition re-sensitized resistant cells to CP-induced cell death

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