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Injecting a drug directly into the Peyronies disease plaque is an appealing alternative to oral medications

It does this by: Activating beta-3 adrenergic receptors stimulates fat breakdown and mobilization Enhancing lipolysis promotes the use of stored fat as energy Inhibiting lipogenesis reduces the formation of new fat cells In early studies, researchers observed that AOD9604 may help increase fat oxidation and improve metabolic flexibility, especially in overweight or obese individuals

doi:10.1007/s11883-022-01022-w

Other aetiologies include 11-hydroxylase deficiency, 3-hydroxysteroid dehydrogenase deficiency, and P450 oxidoreductase deficiency, which can present in both 46, XX and 46, XY individuals