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46 In 2018, a gene therapy employing an allogeneic expression strategy was tested in a clinical trial for patients with LHON, demonstrating both safety and good tolerability

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Lactic acidosis (LA), a feature of MELAS syndrome, arises due to impaired tissue oxygenation, causing overproduction of lactate (Andersen et al

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T-cell exhaustion in HIV infection

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1d and Extended Data Table 1)

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