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On the opposite knowing that the cause for cognitive decline is not AD can help identify other causes of brain dysfunction such as vascular dementia, autoimmune conditions, toxic exposure

Microglial membranes have a range expression of receptors, including neurotransmitter receptors (e.g., glutamatergic, GABAergic, norepinephrine, acetylcholine, cannabinoid) [58], pattern recognition receptors (e.g., Toll-like receptors, NOD-like receptors, and C-type lectin receptors), immunomodulatory receptors, scavenger receptors, cytokine and chemokine receptors [59]

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Presented at the Eur Acad Dermatol Venereol Annual Meeting , Amsterdam, Netherlands, 2014