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Description

The increase in oxidative stress is commonly reported in Alzheimers disease ( Association of memory loss with a parallel increase in the expression of APP in the brain of diabetic control mice suggests an association with Alzheimers disease in the diabetes model

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Blood samples for pharmacokinetic analysis were collected up to 15 min pre-dose (day 1), and at 4, 8, 12, 18, 24, 30, 36, 48, 54, 60, 72, 84, 96 and 120 h post-dose