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This has been shown to be concentration-dependent, as well as consistent across species and myocardial preparations ( Extracellular Ca 2+ influx and L-type Ca 2+ channels The arrhythmic and positive inotropic manifestations of myocardial LCAC superfusion have been reported to increase in amplitude and frequency proportionally with increases in extracellular Ca 2+ concentration ( 2+ superfusion medium ( 2+ acutely evoked by LCAC superfusion was significantly blunted with EGTA chelation of extracellular Ca 2+ ( 2+

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