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This turnover produces byproducts that must be excreted

This does not invalidate the findings but adds a potential source of bias Single-blind only: While the investigator assessing photos was blinded, patients knew whether they received the active serum or saline, which could influence self-reported satisfaction scores No long-term follow-up: The study ended at 6 months

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OPZELURA was studied in two clinical trials through 2 years in participants aged 12 and older with nonsegmental vitiligo on up to 10% of their total body surface area (BSA)