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among these, immunoglobulin genes formed the most prominent group, with half of them exhibiting the highest amplitude of expression alteration among the genes for which the level of transcripts was affected by the peptide (Table 2)

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In conditions of experimental focal ischemia, the action of Semax observed 3 h after the onset of ischemia influenced the expression of several genes that are involved in the regulation of the activity of immune cells: macrophages, neutrophils, and lymphocytes (Figure 3A)

Ultrathin uranyl acetate contrasted sections were imaged with a LEO EM912 AB (Zeiss) equipped with a 2 kCCD camera (TRS, Moorenweis)