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In laboratory animals, curcumin has been shown to play a stimulatory role in ovarian functions and prevents the compromise of ovarian functions caused by cyclophosphamide (CPM), ionizing radiation, and ischemia (Alekseyeva et al., 2011

P., Calderwood, M

123 As CBS and CSE use the same substrates to generate H 2 S, their function is interdependently regulated through substrate/product accumulation/depletion, which will favour one biochemical pathway over the other

Given the pivotal role of T cells in female conception and emerging evidence that BAs modulate T cells differentiation, such an approach may open new avenues for developing microbiota-targeted interventions to enhance female reproductive health