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Therapeutic Opportunities with Pharmacological Inhibition of CD38 with Isatuximab

Helps stimulate oxygen production in the blood , muscles and tissues

Am J Hematol 95:E156e158 Ethics declarations Conflict of interest The authors declare that they have no conflict of interest

Complementary to the above, it has been thought for a long time that only supraphysiological concentrations of IGF-1 are able to activate the IR, as will be further discussed in this manuscript