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In mammalian cells, ER stress leads to an integrated stress response involving the related transmembrane kinases Ire1, Ire1 and PKRlike ER kinase (PERK), and the transmembrane activating transcription factor 6 (ATF6) (Zhang & Kaufman, 2004)

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aeruginosa VAP or its colonization in the tracheobronchus [79], which, in turn, proves that C

Manuscript source: Unsolicited manuscript Peer-review started: October 11, 2019 First decision: November 2, 2019 Article in press: February 17, 2020 Specialty type: Gastroenterology and hepatology Country/Territory of origin: United States Peer-review reports scientific quality classification Grade A (Excellent): A Grade B (Very good): B Grade C (Good): C, C Grade D (Fair): 0 Grade E (Poor): 0 P-Reviewer: Cure E, De Ponti F, Lei YC, Qadir MI S-Editor: Wang YQ L-Editor: A E-Editor: Wu YXJ Contributor Information Laura Rotundo, Department of Medicine, Rutgers New Jersey Medical School, Newark, NJ 07103, United States