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Most compelling evidence is from animal models

doi: 10.1038/nature21031 Summary Keywords last eukaryotic common ancestor, iron sulfur cluster biogenesis, sulfur mobilization machinery, iron sulfur cluster machinery, eukaryotic evolution, cytosolic iron/suphur cluster assembly machinery Citation Tsaousis AD (2019) On the Origin of Iron/Sulfur Cluster Biosynthesis in Eukaryotes