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It was established that naloxone produces a favorable action on respiratory mechanics, pulmonary function test parameters, and oxygen metabolism of cases with respiratory failure, and it can considerably improve the general state of the body [81]

Clin Radiol 2021;76:942.e1-6

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First, the p38 inhibitor SB202190, ERK1/2 inhibitor SCH772984, and AKT inhibitor MK-22062 were found to block the upregulated COX-2 expression induced by Giardia infection, revealing an association between p38/ERK/AKT signaling and COX-2