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The strategies to address senescent cells and replenish exhausted stem cells during the aging process, as well as supplementing metabolic substances like NAD+, gene therapy, or epigenetic approaches to mitigate aging, are different because they aim to promote the repair of senescent cells rather than inducing their apoptosis (Covarrubias et al., 2020

One caution on identity: TB-500 (the fragment) and full-length TB-4 (43 amino acids) are related but not interchangeable, and product labels blur the two routinely. The stronger anti-scarring and tissue-remodeling claims come from full-length TB-4 research, not the isolated fragment