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Testosterone Enanthate 250mg administered every two to three weeks, with a maintenance dose of 250mg given every three to six weeks thereafter

Known FcRn expression sites include the bloodbrain barrier, the placenta, the liver, the genital tract, the skin, muscle tissue, the kidneys, the bladder, the intestines and stomach, the eyes, the lung and nasal epithelium, certain immune cells, and certain endocrine tissue

In patients with locally advanced, metastatic, and/or refractory solid tumors and hematological malignancies, CB839 is being evaluated in open-label phase I clinical trials (NCT02071862, NCT02071888, NCT02771626)

Notably, studies on primary intestinal epithelial cells show that 2m-targeting mAbs may impair viral infection [376]