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The role of IGF-1 in the CNS can vary across different stages of life and disease states (see Fig

PubMed Kannengiesser, K., Maaser, C., Heidemann, J., Luegering, A., Ross, M., Brzoska, T., Bohm, M., Luger, T.A., Domschke, W., Kucharzik, T

High erythrocyte levels of the n-6 polyunsaturated fatty acid linoleic acid are associated with lower risk of subsequent rheumatoid arthritis in a southern European nested case-control study

Unlike earlier reviews, this synthesis integrates historical context, current applications, mechanistic insights, safety considerations, and future prospects to provide a holistic perspective