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doi: 10.3389/fped.2020.613641 101 LuC

USA 103 , 714719 (2006)

Beta-lactam antibiotics offer neuroprotection by increasing glutamate transporter expression

That short activity window is part of why once-daily dosing is often used in educational referencesone consistent daily pulse can be enough to support a physiologic-style rhythm, especially when paired with steady sleep timing and nutrition consistency (since sleep, meal timing, and training load can all influence GH signaling day to day)