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One aspect of the invention pertains to treating an NNMT-expressing cancer, such as glioblastoma, by administering a therapeutically effective amount of one or more cations of the invention with concurrent administration of one or more cations chosen from Tables 3a and 3b

Another question for future studies is which organ-specific aging proteins are causal drivers of aging, given that multiple plasma proteins have been shown to directly modulate aging phenotypes 8