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In fact, it is not only tumor microenvironments which can educate immune cells since for instance, the GM-CSF can license murine and human monocytes toward their immunosuppressive phenotypes through the PI3K/AKT/mTOR signaling pathway [90]

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However, some studies have shown inadequate levels of copper and manganese in the hippocampus in patients with MTLE and hippocampus sclerosis (MTLS-HS), while iron levels remain unaltered ( In summary, abnormal iron metabolism and distribution in the brain of epileptic patients might be one of the reasons for the occurrence and development of epilepsy

176 (33, 1226), GGT 46 (11-1579), platelets 282x10^3 (24-652), IgG 1380 mg/dL (480-5171), +autoantibody 57%, LSM 6.2 kPa (3.5-63.9)