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This is interesting too since chronic inflammation has emerged as part of the pathogenesis of PCOS

Baales-luna M, Figueroa-vega N, Marn-aragn CI, Perez-luque E, Ibarra-reynoso L, Gallardo-blanco HL, Lpez-aguilar I, Malacara JM (2020) Associations of nicotidamide- N -methyltransferase, FTO, and IRX3 genetic variants with body mass index and resting energy expenditure in Mexican subjects