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However, microtubule inhibitors are highly non-specific and affect many additional processes, including vesicular trafficking, mitosis, and immune cell functions

Alternatively, contralateral reorganization could reflect injury-induced plasticity within the spinal cord or supraspinal influences

Inhibition of PKM2 caused by oxidative modification of the cysteine residue at position 358 [145] contributes to maintain cellular anti-oxidant responses by diverting the glucose flux into the pentose phosphate pathway thereby generating sufficient reducing potential for the detoxification of ROS [146]

doi: 10.1016/j.retram.2016.10.003 58