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Trevisson E, Morbidoni V, Forzan M, et al

Reduce application frequency from daily to every other day

Effects of melatonin on fine structures and extracellular matrix proteins of cancer cell lines

Based on the % change in NO, the l-Cit group revealed higher changes than PL group in PRE to IP ( P = 0013, 45 %, 048 Umol/l, 95 % CI (0625, 1584)), PRE to 10P ( P = 004, 4 %, 044 Umol/l, 95 % CI (0454, 1334)) and PRE to 30P ( P = 0042, 4 %, 041 Umol/l, 95 % CI (0288, 1108)) (Fig