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IMQ-induced psoriatic mouse model Six-week-old female BALB/c mice or C57BL/6 mice, along with NRF2 knockout mice (acquired from the Model Animal Research Center of Nanjing University), were randomly grouped and maintained in an SPF environment, subjected to a 12-hour light/dark cycle, and provided with unrestricted access to food and water

Diseases caused by Acanthamoeba include keratitis and granulomatous amoebic encephalitis (GAE)

Eight- to twelve-week-old C57BL/6J male mice were purchased from Charles River (UK) and acclimatized to the local animal unit for 1 week before the experiment

Here, we address this gap by reverse engineering of the BH3-only protein BNIP3