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Emerging resistance to currently available antifungal drugs and a deficiency in discovery of new ones engender urgency for development of new antifungal agents and/or alternative therapies for control of fungal pathogens [37]

Statements Author contributions CM: Conceptualization, Visualization, Writingoriginal draft, Writingreview and editing

The administration of ginger extract at doses of 100, 200, and 400mg/kg resulted in a reduction in levels of oxidant stress factors such as MDA and PCO, as well as acute inflammatory markers including MPO, TNF-, and PGE2, in rats with acetic acid-induced UC [230]

In contrast, melatonin levels were reduced in the tissues examined, particularly so in the brain