glutathione synthetase deficiency usmle

glutathione synthetase deficiency usmle HMP Shunt - Biochemistry A very common USMLE Step

Name: glutathione synthetase deficiency usmle HMP Shunt - Biochemistry A very common USMLE Step
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A very common USMLE Step 2 CK trap macrocytic anemia in alcohol use, and many jump to the wrong deficiency. Chronic alcohol use + macrocytosis pancytopenia think folate X linked recessive NADPH RBCs can't handle oxidative stress NADPH keeps glutathione active protects RBCs Triggers ( Amino Acid Metabolism and Heritable Disorders of Degradation Cell Biology, Genetics, and Biochemistry for Pre Clinical Students Glutathione synthesis: A two step pathway. Homeostasis of cellular Download Scientific Diagram

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