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Contraindications Based on Mechanism Active mental health crisis or suicidal ideation (unproven intervention should never delay evidence-based emergency care) Pregnancy or breastfeeding (no safety data, potential for developmental effects given neuroprotective/neuroplastic actions) Bleeding disorders (BPC-157 affects thrombocyte function) Immune system disorders (concerns about potential immune reactions) Frequently Asked Questions What is BPC-157 and where does it come from

The study identified increased proportions of pro-inflammatory and mesenchymal fibroblast subpopulations, elevated p16 protein and SA--galactosidase-positive cells, and enhanced SASP gene expression in keloid tissue

Pevec et al., 2010) and worsening, and immunosuppression (Sikiric et al., 2003)