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Successful treatment depends on a thorough clinical assessment, which includes evaluation of tissue condition, infection and inflammation status, exudate characteristics, wound edges, surrounding skin, and pain

Endocrine side-effects of anti-cancer drugs: mAbs and pituitary dysfunction: clinical evidence and pathogenic hypotheses

it is an endogenous fragment, and one line of thinking holds that it may be liberated from larger proteins for example, during tissue injury when extracellular-matrix proteins such as collagen and SPARC (osteonectin) are proteolytically degraded