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Select estrogens within the complex formulation of conjugated equine estrogens (Premarin) are protective against neurodegenerative insults: implications for a composition of estrogen therapy to promote neuronal function and prevent Alzheimers disease

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The reason for this restriction is that as previously described, the age-related decline in function of the GH neuroendocrine axis is accepted as being a normal part of aging, even though it is progressively detrimental to many aspects of body function