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Autophagy can also maintain healthy stem cell niches

reuteri NK33 can activate microglial cell infiltration into the hippocampus and induce hippocampal brain-derived neurotrophic factor (BDNF) expression and cAMP-response element binding protein (CREB) phosphorylation in IS-exposed mice as well as LPS-stimulated SH-SY5Y cells by suppressing the activation of the NF-B pathway and HPA axis, thus suggesting that NK33 alleviated the suppression of NF-B-mediated BDNF expression in the hippocampus, with the regulation of LPS infiltration into the brain, leading to the attenuation of anxiety and depression

(12) D Philp, M Nguyen, B Scheremeta, et al (2004) Thymosin beta4 increases hair growth by activation of hair follicle stem cells FASEB Journal, 2004 Feb, Volume 18 (Issue 2), Pages 385-7

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