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Disruption of metal transport proteins can lead to both toxic accumulation and essential deficiencies (Zheng and Monnot, 2012).Chelation therapies and metal modulating nutraceuticals are currently under investigation as potential therapeutic options in AD (Sensi et al., 2018)

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They only become available to compound if an FDA advisory committee recommends them and the FDA signs off, and that committee turned down every peptide it reviewed the last time, in 2024