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Immunohistochemical staining for Nrf2, NQO1, and HO-1 expression on knee joint histological sections demonstrated that metformin administration significantly increased the numbers of Nrf2, NQO1, and HO-1-positive chondrocytes compared to those in OA group (Fig

A review of traditional Chinese medicine on treatment of diabetic nephropathy and the involved mechanisms

doi: 10.1007/s10165-012-0752-4 120 FlytlieHAHvidMLindgreenEKofod-OlsenEPetersenELJrgensenAet al

Moreover, the plant extract had an antilithic effect on rats on a glycolate diet through the decrease in oxalate retention time in the kidneys and more excretion into urine [80]