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This can mislead both the patient and the treating doctor into thinking vitamin B12 was not the issue

A 2019 proof-of-concept study in Human Reproduction (Romero-Ruiz et al.) provided the earlier human data: kisspeptin treatment induced gonadotropic responses and rescued ovulation in a subset of women with PMOS, demonstrating direct clinical translation from the animal work

As much as having sex in the water always seems like a good idea, the water washes away the vaginas natural lubrication, leading to vaginal dryness, which can make penetration feel uncomfortable

Insulin also increases the production of testosterone, which is converted to even more estrogen by belly fat