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A2780 cells were seeded at a density of 3x10^5 cells per mL in a 6-well format and allowed to adhere overnight

Loperamide (Imodium) and diphenoxylate (Lomotil), an opioid agonist, are first-line medical treatments for chemotherapy-induced diarrhea

The low pH of these acids destabilizes the copper peptide complex, potentially reducing its effectiveness and increasing irritation risk

For research-grade peptides like those available through Real Peptides, where purity and consistency are verified at every batch, wasting active compound on the wrong administration route defeats the purpose of sourcing high-quality material in the first place