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Ferulic Acidsupercharges the effects ofglutathione

J Biol Chem 275:1325913265 Brandsma D, Kerklaan BM, Diras V, Altintas S, Anders CK, Ballester MA, Gelderblom H, Soetekouw PMMB, Gladdines W, Lonnqvist F et al (2014) Phase 1/2a study of glutathione pegylated liposomal doxorubicin (2b3-101) in patients with brain metastases (BM) from solid tumors or recurrent high grade gliomas (HGG)

As aforementioned, we observed accelerated roGFP2 re-oxidation in the WT, but not in dsbA , when adding monothiols to the cells and the opposite effect for GSSG, compensating the lack of DsbA, raising the question whether DsbB is somehow regulated by glutathione

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