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10.1016/S0168-8278(98)80211-0

(78) previously established that heat shock protein beta-1 (HSPB1) is a negative regulator of ferroptosis in cancer cells

Therefore, methyl groups are a necessary trigger compound for DNA activation, renewal of essential proteins, and cell rejuvenation

Few functional assays tried to correlate the expression and/or activity of MST with the cancer cells features, however, using inhibiting and silencing assays, some studies proved that MST activity is important for cancer cells proliferation (98, 99)